Plasma B-Type Natriuretic Peptide Role for Evaluation of Pathogenetic Condition and Outcome of Acute Coronary Syndrome

Objective:To study the role of plasma B-type natriuretic peptide to evaluate the pathogenetic condition and outcome of acute coronary syndrome.Methods:81 patients with ACS(observation group) and 30 health examination persons(controlling group) were enrolled in this study.Plasma levels of BNP were detected in 24 hours after hospitalization and coronary angiography were performed for detecting the affected coronary arteries in a week.Results:Plasma levels of BNP of the observation group were higher than those of the controlling group(P0.01).The correlation was positive between the number of affected coronary arteries and the levels of BNP(P0.01).Conclusion:BNP was an important factor in the pathogenesy of ACS;the levels of BNP may reflect the severity of ACS,and BNP can be an important index to evaluate the pathogenetic condition and outcome.Monitoring the BNP level effectively in clinic possesses is considered significant significance to diagnose exactly and reasonable treatment for acute coronary syndrome.