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2008•Medical Journal of Chinese People's HealthRequires access

A study of risperidone combining with venlafaxine in the treatment of somatization disorder

Wang Quan-ying

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Abstract

Objective:To explore the efficacy and safety of risperidone combining with venlafaxine in the treatment of somatization disorder.Methods:A total of 60 outpatients who met the criteria of CCMD-3 for somatization disorder were assigned to therapeutic group(n=30)and control group(n=30)for the treatment of 6 weeks.Therapeutic group was given venlafaxine in addition to risperidone,and control group was venlafaxine alone.The clinical effect was assessed with HAMD and HAMA at the end of 2nd,4th and 6th week.The adverse reaction was evaluated by TESS.Results: The therapeutic efficacy in venlafaxine plus risperidone group was significantly higher than that in control group.Conclusions: Venlafaxine plus risperidone has better effect in the treatment of somatization disorder than venlafaxine only.

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What this paper is about

Objective:To explore the efficacy and safety of risperidone combining with venlafaxine in the treatment of somatization disorder.Methods:A total of 60 outpatients who met the criteria of CCMD-3 for somatization disorder were assigned to therapeutic group(n=30)and control group(n=30)for the treatment of 6 weeks.Therapeutic group was given venlafaxine in addition to risperidone,and control group was venlafaxine alone.The clinical effect was assessed with HAMD and HAMA at the end of 2nd,4th and 6th week.The adverse reaction was evaluated by TESS.Results: The therapeutic efficacy in venlafaxine plus risperidone group was significantly higher than that in control group.Conclusions: Venlafaxine plus risperidone has better effect in the treatment of somatization disorder than venlafaxine only.

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Available abstract

Objective:To explore the efficacy and safety of risperidone combining with venlafaxine in the treatment of somatization disorder.Methods:A total of 60 outpatients who met the criteria of CCMD-3 for somatization disorder were assigned to therapeutic group(n=30)and control group(n=30)for the treatment of 6 weeks.Therapeutic group was given venlafaxine in addition to risperidone,and control group was venlafaxine alone.The clinical effect was assessed with HAMD and HAMA at the end of 2nd,4th and 6th week.The adverse reaction was evaluated by TESS.Results: The therapeutic efficacy in venlafaxine plus risperidone group was significantly higher than that in control group.Conclusions: Venlafaxine plus risperidone has better effect in the treatment of somatization disorder than venlafaxine only.

Key concepts: Venlafaxine, Risperidone, Somatization, Hamd, Somatization disorder, Medicine, Adverse effect, Psychiatry

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