2010•Inner Mongolia Medical JournalRequires access

Therapeutic Effect of Budesonide and Formoterol Fumarate Powder for Inhalation in Children's Seasonal Asthma

Xin Wang

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Abstract

Objective:To study the effcts of clinical efficacy and pulmonary function of inhaled dry-powder budesonide /fomoterol in the treatment of Children's Seasonal Asthma.Methods:In randomized,open,paralled-group trail,62 cases of Children's Seasonal Asthma were divided into study group(30 cases) and control group(32 cases),all patients in study group inspired Budesonide Formoterol Sing inspirator[80 μg(Budesonide)/4.5 μg(fomoterol)/stuff] 2 times/d,when symptoms manifested used inspired Budesonide Formoterol Sing inspirator[80 μg(Budesonide)/4.5 μg(fomoterol)/stuff] to reliever therapy;all patients in group control inspired Budesonide(100 μg/snuff),1~2 times/d,according to demand inspirator Terbutaline Sulphate Aerosol.all patients adverse-events,by using Spray for inhalation Pulmicort Respulses and Bricanyl.Clinical symptoms,lung function and hospital expenses were observed.Results:Two group symptom has improved.the emergency treatment and hospital expenses was significantly littler in study group ,(z=-3.775,P=0.000)and(z=-5.451,P=0.000);The treatment with budesonide /fomoterol turbulaler resulted in remarkably improvement asthma symptom,and lung function were notably increased after 12 Weeks of treatment and the increased value of each index of pulmonary function had staistical significance between study and control group(P0.05).Conclusion::Budesonide /fomoterol turbulaler possesses the advantage of in treatment of patients to reduce emergency treatment and hospital expenses,to improve pulmonary function with Children's Seasonal Asthma.

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Objective:To study the effcts of clinical efficacy and pulmonary function of inhaled dry-powder budesonide /fomoterol in the treatment of Children's Seasonal Asthma.Methods:In randomized,open,paralled-group trail,62 cases of Children's Seasonal Asthma were divided into study group(30 cases) and control group(32 cases),all patients in study group inspired Budesonide Formoterol Sing inspirator[80 μg(Budesonide)/4.5 μg(fomoterol)/stuff] 2 times/d,when symptoms manifested used inspired Budesonide Formoterol Sing inspirator[80 μg(Budesonide)/4.5 μg(fomoterol)/stuff] to reliever therapy;all patients in group control inspired Budesonide(100 μg/snuff),1~2 times/d,according to demand inspirator Terbutaline Sulphate Aerosol.all patients adverse-events,by using Spray for inhalation Pulmicort Respulses and Bricanyl.Clinical symptoms,lung function and hospital expenses were observed.Results:Two group symptom has improved.the emergency treatment and hospital expenses was significantly littler in study group ,(z=-3.775,P=0.000)and(z=-5.451,P=0.000);The treatment with budesonide /fomoterol turbulaler resulted in remarkably improvement asthma symptom,and lung function were notably increased after 12 Weeks of treatment and the increased value of each index of pulmonary function had staistical significance between study and control group(P0.05).Conclusion::Budesonide /fomoterol turbulaler possesses the advantage of in treatment of patients to reduce emergency treatment and hospital expenses,to improve pulmonary function with Children's Seasonal Asthma.

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Available abstract

Objective:To study the effcts of clinical efficacy and pulmonary function of inhaled dry-powder budesonide /fomoterol in the treatment of Children's Seasonal Asthma.Methods:In randomized,open,paralled-group trail,62 cases of Children's Seasonal Asthma were divided into study group(30 cases) and control group(32 cases),all patients in study group inspired Budesonide Formoterol Sing inspirator[80 μg(Budesonide)/4.5 μg(fomoterol)/stuff] 2 times/d,when symptoms manifested used inspired Budesonide Formoterol Sing inspirator[80 μg(Budesonide)/4.5 μg(fomoterol)/stuff] to reliever therapy;all patients in group control inspired Budesonide(100 μg/snuff),1~2 times/d,according to demand inspirator Terbutaline Sulphate Aerosol.all patients adverse-events,by using Spray for inhalation Pulmicort Respulses and Bricanyl.Clinical symptoms,lung function and hospital expenses were observed.Results:Two group symptom has improved.the emergency treatment and hospital expenses was significantly littler in study group ,(z=-3.775,P=0.000)and(z=-5.451,P=0.000);The treatment with budesonide /fomoterol turbulaler resulted in remarkably improvement asthma symptom,and lung function were notably increased after 12 Weeks of treatment and the increased value of each index of pulmonary function had staistical significance between study and control group(P0.05).Conclusion::Budesonide /fomoterol turbulaler possesses the advantage of in treatment of patients to reduce emergency treatment and hospital expenses,to improve pulmonary function with Children's Seasonal Asthma.

Key concepts: Budesonide, Medicine, Asthma, Inhalation, Formoterol, Budesonide/formoterol, Adverse effect, Pulmonary function testing

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