CT-guided percutaneous biopsy of musculoskeletal lesions

Objective To evaluate the clinical applications of CT-guided percutaneous fine needle aspiration biopsy of musculoskeletal lesions and the role of laser-guided device for CT biopsy in musculoskeletal lesions.Methods There were 165 cases with CT-guided percutaneous fine needle aspiration biopsy of musculoskeletal lesions including 142 cases of bone lesions and 23 cases of soft tissue lesions. 149 cases were proved pathologically by surgery,open biopsy or had clinical follow-up information.Results The accuracy of CT-guided fine needle aspiration biopsy was 75.2%(124/165).The accuracy rates for bone and soft tissue biopsies were 73.2%(104/142)and 87.0%(20/23)respectively.The accuracy rate for laser-guided biopsy was 80.6%(29/36).The biopsy accuracy rates were 73.8%(96/130)with Ackermann needle and 80.0%(28/35)with fine needle aspiration(FNA).The accuracy rates for big lesions(diameter3 cm)and small lesions(diameter≤3 cm)were 80.6%(79/98)and 67.2% (45/67),respectively(P0.05).Conclusion CT-guided percutaneous fine needle aspiration biopsy is a safe,simple and effective method for the diagnosis and differential diagnosis of muscnloskeletal lesions.The biopsy for the big lesion is superior to the small one.The diagnostic accuracy can be improved with laser- guided CT biopsy for small lesions.