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Clinical study on therapy of acute respiratory distress syndrome with ulinastatin

Wen Yu-ming

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Abstract

Objective To evaluate the effect of ulinastatin on the therapy of acute respiratory distress syndrome(ARDS).Methods Thirty-six patients with ARDS were randomly divided into experimental group(18 cases) and control group(18 cases).We observed the change of the parameters of arterial blood gas,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score and mortality between the two groups,before and after treatment.Results The parameters of arterial blood gas,APACHE Ⅱ score were obviously superior to those of the control group.The mortality in the experimental group was significantly lower than that in the control group.Conclusion Ulinastatin can obviously improve the parameters of arterial blood gas,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score of the patients with ARDS.It also has obvious therapeutis effect on the prevention and cure of multiorgems distress syndrome(MODS) and decreasing the mortality of the patients with ARDS.

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What this paper is about

Objective To evaluate the effect of ulinastatin on the therapy of acute respiratory distress syndrome(ARDS).Methods Thirty-six patients with ARDS were randomly divided into experimental group(18 cases) and control group(18 cases).We observed the change of the parameters of arterial blood gas,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score and mortality between the two groups,before and after treatment.Results The parameters of arterial blood gas,APACHE Ⅱ score were obviously superior to those of the control group.The mortality in the experimental group was significantly lower than that in the control group.Conclusion Ulinastatin can obviously improve the parameters of arterial blood gas,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score of the patients with ARDS.It also has obvious therapeutis effect on the prevention and cure of multiorgems distress syndrome(MODS) and decreasing the mortality of the patients with ARDS.

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Available abstract

Objective To evaluate the effect of ulinastatin on the therapy of acute respiratory distress syndrome(ARDS).Methods Thirty-six patients with ARDS were randomly divided into experimental group(18 cases) and control group(18 cases).We observed the change of the parameters of arterial blood gas,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score and mortality between the two groups,before and after treatment.Results The parameters of arterial blood gas,APACHE Ⅱ score were obviously superior to those of the control group.The mortality in the experimental group was significantly lower than that in the control group.Conclusion Ulinastatin can obviously improve the parameters of arterial blood gas,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score of the patients with ARDS.It also has obvious therapeutis effect on the prevention and cure of multiorgems distress syndrome(MODS) and decreasing the mortality of the patients with ARDS.

Key concepts: Ulinastatin, ARDS, Medicine, Acute respiratory distress, Arterial blood, APACHE II, Mortality rate, Anesthesia

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