2009Journal of North Sichuan Medical CollegeRequires access

Analysis on Nipple Discharge of 127 Cases

MA Kui-yuan

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Abstract

Objective To investigate reasonable diagnostic and treatment for primary disease of nipple discharge.Methods The characteristics of 127 patients with nipple discharge were retrospective analyzed.Results Following retrospective review,39 cases of bloody discharge,42 cases of serous bloody discharge and 46 cases of serous discharge were found.Through the pathological diagnosis,103 cases(81.1%) of benignancy,21(16.5%) cases of breast cancer and 3(2.4%) cases of atypical duct hyperplasia were discovered.Breast cancer in patients with bloody nipple discharge was 23.5%(19/81),and 4.3%(2/46) in those with non-bloody discharge.All patients were treated with surgery,106 patients underwent simply the lobe section of the breast gland surgery,14 patients underwent simple mastectomy and sentinel lymph node dissection,7 patients underwent modified radical mastectomy.After 6 months following up,recrudescence of nipple discharge,cancer and cancerous metastasis were not found.Conclusions Pathological examination diagnosis is the most important way to determine the cause of nipple discharge.Surgical treatment of the primary disease of nipple discharge is effective measure to prevent early breast cancer and precancerous lesions of breast.

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Objective To investigate reasonable diagnostic and treatment for primary disease of nipple discharge.Methods The characteristics of 127 patients with nipple discharge were retrospective analyzed.Results Following retrospective review,39 cases of bloody discharge,42 cases of serous bloody discharge and 46 cases of serous discharge were found.Through the pathological diagnosis,103 cases(81.1%) of benignancy,21(16.5%) cases of breast cancer and 3(2.4%) cases of atypical duct hyperplasia were discovered.Breast cancer in patients with bloody nipple discharge was 23.5%(19/81),and 4.3%(2/46) in those with non-bloody discharge.All patients were treated with surgery,106 patients underwent simply the lobe section of the breast gland surgery,14 patients underwent simple mastectomy and sentinel lymph node dissection,7 patients underwent modified radical mastectomy.After 6 months following up,recrudescence of nipple discharge,cancer and cancerous metastasis were not found.Conclusions Pathological examination diagnosis is the most important way to determine the cause of nipple discharge.Surgical treatment of the primary disease of nipple discharge is effective measure to prevent early breast cancer and precancerous lesions of breast.

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Available abstract

Objective To investigate reasonable diagnostic and treatment for primary disease of nipple discharge.Methods The characteristics of 127 patients with nipple discharge were retrospective analyzed.Results Following retrospective review,39 cases of bloody discharge,42 cases of serous bloody discharge and 46 cases of serous discharge were found.Through the pathological diagnosis,103 cases(81.1%) of benignancy,21(16.5%) cases of breast cancer and 3(2.4%) cases of atypical duct hyperplasia were discovered.Breast cancer in patients with bloody nipple discharge was 23.5%(19/81),and 4.3%(2/46) in those with non-bloody discharge.All patients were treated with surgery,106 patients underwent simply the lobe section of the breast gland surgery,14 patients underwent simple mastectomy and sentinel lymph node dissection,7 patients underwent modified radical mastectomy.After 6 months following up,recrudescence of nipple discharge,cancer and cancerous metastasis were not found.Conclusions Pathological examination diagnosis is the most important way to determine the cause of nipple discharge.Surgical treatment of the primary disease of nipple discharge is effective measure to prevent early breast cancer and precancerous lesions of breast.

Key concepts: Medicine, Nipple discharge, Serous fluid, Breast cancer, Surgery, Mastectomy, Bloody, Modified Radical Mastectomy

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