ScholarLens Back to search
2008•Jiangsu Medical JournalRequires access

Serum cystatin C as an early diagnostic marker in children with renal diseases

GE Gaoxi

Open publisher page 0 citations

Abstract

Objective To compare the sensitivity of serum cystatin C(CYC) with serum creatinine(SCr) and blood urea in children with renal disease and investigate the CYC level in healthy children during different stages of diseases. Methods Sixty-four children with renal diseases were collected in this study. Serum CYC was measured by microparticle enhanced nephelometry,serum SCr and urea were measured by enzyme-analysis method. The results were compared with regard to their differences in sensitivity. Meanwhile, 106 healthy children aged from 0 to 14 years old were also studied as normal controls to determine the normal range of CYC. Results The sensitivity of CYC in patient group was 59.4%(38/64),which was higher than that of both SCr (25.0%, 16/64) and urea (12.5%,8/64) (P0.01).Conclusion CYC is more sensitive than SCr and Urea in the early diagnosis of renal disease.

About this research paper

What this paper is about

Objective To compare the sensitivity of serum cystatin C(CYC) with serum creatinine(SCr) and blood urea in children with renal disease and investigate the CYC level in healthy children during different stages of diseases. Methods Sixty-four children with renal diseases were collected in this study. Serum CYC was measured by microparticle enhanced nephelometry,serum SCr and urea were measured by enzyme-analysis method. The results were compared with regard to their differences in sensitivity. Meanwhile, 106 healthy children aged from 0 to 14 years old were also studied as normal controls to determine the normal range of CYC. Results The sensitivity of CYC in patient group was 59.4%(38/64),which was higher than that of both SCr (25.0%, 16/64) and urea (12.5%,8/64) (P0.01).Conclusion CYC is more sensitive than SCr and Urea in the early diagnosis of renal disease.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To compare the sensitivity of serum cystatin C(CYC) with serum creatinine(SCr) and blood urea in children with renal disease and investigate the CYC level in healthy children during different stages of diseases. Methods Sixty-four children with renal diseases were collected in this study. Serum CYC was measured by microparticle enhanced nephelometry,serum SCr and urea were measured by enzyme-analysis method. The results were compared with regard to their differences in sensitivity. Meanwhile, 106 healthy children aged from 0 to 14 years old were also studied as normal controls to determine the normal range of CYC. Results The sensitivity of CYC in patient group was 59.4%(38/64),which was higher than that of both SCr (25.0%, 16/64) and urea (12.5%,8/64) (P0.01).Conclusion CYC is more sensitive than SCr and Urea in the early diagnosis of renal disease.

Key concepts: Nephelometry, Creatinine, Cystatin C, Medicine, Urea, Internal medicine, Renal function, Endocrinology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Serum cystatin C as an early diagnostic marker in children with renal diseases — Research Paper | ScholarLens