Experimental Study on Effects of Wolfberry on Antioxidant Function in Aged Mice

Objective To study the effects of wolfberry on antioxidant function in aged mice.Methods According to the method for the assessment of antioxidative function in Technogical Specification for Inspection and Evaluation of Health Food (GB/T15193-2003),40 KM aged mice were randomly divided into a control group and three treated groups,in which the mice were administered by gavage with wolfberry at the doses of 2.50 g/kg·bw,5.00 g/kg·bw,and 10.00 g/kg·bw respectively once every day for 30 days.The content of blood MDA and the activities of serum SOD and GSH-Px were determined by the colorimetric method introduced in the protocols of related reagent kit.Results Compared with that of control group,the MDA content in the blood significantly decreased and serum SOD activity significantly increased in the mice of high dosage group (P0.05).The serum GSH-Px activity was not affected significantly in each dosage group (P0.05).Conclusions In the present test condition,wolfberry can improve the antioxidant function in aged mice.