ScholarLens Back to search
2012•Jiepou kexue jinzhanRequires access

The Relationship of HR-HPV33 and HPV52 infection with cervical diseases

Jianhua Li

Open publisher page 1 citations

Abstract

Objective To explore the relationship of the high-risk human papillomavirus(HPV) subtypes 33 and 52 with cervial diseases. Methods DNA extraction, PCR application and flow-through hybridization and HE staining were used to analyse the relationship of HPV 33 and 52 with cervial diseases in 194 cases of HPV 33 and 52-positive cervical diseases. Results 25 cases were benign cervical diseases, and 114 cases were cervical intraepithelial neoplasia(CIN) and 55 cases were malignant cervical tumour in total 194 cases of HPV 33 and 52-positive cervical diseases. By using χ2 test we found that the positive rate of CIN and malignant cervical tumour was much higher than that of benign cervical diseases statistically (p0.05). Conclusion HPV 33 and 52-positive cervical patients are more likely to develop cervical diseases, HPV33 and HPV52 are the pathogenic genotypes of malignant cervical diseases.

About this research paper

What this paper is about

Objective To explore the relationship of the high-risk human papillomavirus(HPV) subtypes 33 and 52 with cervial diseases. Methods DNA extraction, PCR application and flow-through hybridization and HE staining were used to analyse the relationship of HPV 33 and 52 with cervial diseases in 194 cases of HPV 33 and 52-positive cervical diseases. Results 25 cases were benign cervical diseases, and 114 cases were cervical intraepithelial neoplasia(CIN) and 55 cases were malignant cervical tumour in total 194 cases of HPV 33 and 52-positive cervical diseases. By using χ2 test we found that the positive rate of CIN and malignant cervical tumour was much higher than that of benign cervical diseases statistically (p0.05). Conclusion HPV 33 and 52-positive cervical patients are more likely to develop cervical diseases, HPV33 and HPV52 are the pathogenic genotypes of malignant cervical diseases.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the relationship of the high-risk human papillomavirus(HPV) subtypes 33 and 52 with cervial diseases. Methods DNA extraction, PCR application and flow-through hybridization and HE staining were used to analyse the relationship of HPV 33 and 52 with cervial diseases in 194 cases of HPV 33 and 52-positive cervical diseases. Results 25 cases were benign cervical diseases, and 114 cases were cervical intraepithelial neoplasia(CIN) and 55 cases were malignant cervical tumour in total 194 cases of HPV 33 and 52-positive cervical diseases. By using χ2 test we found that the positive rate of CIN and malignant cervical tumour was much higher than that of benign cervical diseases statistically (p0.05). Conclusion HPV 33 and 52-positive cervical patients are more likely to develop cervical diseases, HPV33 and HPV52 are the pathogenic genotypes of malignant cervical diseases.

Key concepts: Medicine, Cervical intraepithelial neoplasia, Cervical cancer, Human papillomavirus, Internal medicine, HPV infection, Gastroenterology, Pathology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The Relationship of HR-HPV33 and HPV52 infection with cervical diseases — Research Paper | ScholarLens