Feasibility and safety of pterygium excision combined with autologous limbal stem cell transplantation in the treatment of pterygium
LI Wang-hu
Abstract
LI Wang-hu
Abstract
Objective To explore the feasibility and safety of pterygium excision combined with autologous limbal stem cell transplantation in the treatment of pterygium. Methods 90 cases with pterygium from May 2012 to January 2014 in our hospital were selected and randomly divided into the study group and the control group,45 cases in each group.The control group was treated with simple pterygium excision,the study group was treated with pterygium excision combined with autologous limbal stem cell transplantation.Postoperative recovery in two groups was observation,the efficacy and the recurrence rate after surgery in six months and one year in two groups was compared. Results The corneal epithelial healing time,hospital stay,duration of unwell symptoms in the study group was shorter than that in the control group,with significant difference(P0.05).The cure rate of the study group after surgery in six months and one year was higher than that of the control group,with significant difference(P0.05).The recurrence rate of the study group after surgery in six months and one year was lower than that of the control group,with significant difference(P0.05). Conclusion The effect of pterygium excision combined with autologous limbal stem cell transplantation in the treatment of pterygium is significant,the recurrence rate is low,and it is safe and reliable,which is worthy of clinical promotion and application.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective To explore the feasibility and safety of pterygium excision combined with autologous limbal stem cell transplantation in the treatment of pterygium. Methods 90 cases with pterygium from May 2012 to January 2014 in our hospital were selected and randomly divided into the study group and the control group,45 cases in each group.The control group was treated with simple pterygium excision,the study group was treated with pterygium excision combined with autologous limbal stem cell transplantation.Postoperative recovery in two groups was observation,the efficacy and the recurrence rate after surgery in six months and one year in two groups was compared. Results The corneal epithelial healing time,hospital stay,duration of unwell symptoms in the study group was shorter than that in the control group,with significant difference(P0.05).The cure rate of the study group after surgery in six months and one year was higher than that of the control group,with significant difference(P0.05).The recurrence rate of the study group after surgery in six months and one year was lower than that of the control group,with significant difference(P0.05). Conclusion The effect of pterygium excision combined with autologous limbal stem cell transplantation in the treatment of pterygium is significant,the recurrence rate is low,and it is safe and reliable,which is worthy of clinical promotion and application.
Key concepts: Pterygium, Medicine, Surgery, Significant difference, Transplantation, Limbal stem cell, Clinical efficacy, Stem cell