2005•Zhongguo tengtong yixue zazhiRequires access

POSTOPERATTVE PCEA WITH SUFENTANIL PLUS ROPIVACAINE

Xin Wu

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Abstract

Objective: To observe the analgesic and side effects of sufentanil or fentanyl combined with ropivacaine in postoperative patients with controlled epidural analgesia (PCEA). Methods:100 patients,ASA I~II,under going abdominal operation, were randomly divided into two groups. Sufentanil 0.5μg/ml or fentanyl 2 μg/ml with 0.12% ropivacaine were given epidurally after surgery, respectively, with basal dose of 4 ml/h, PCA dose of 2ml and lockout time of 20 min. Postoperative analgesic effects, PCEA pump usage,drug comsumption and side effects were observed within 48 hr. Results: Analgesic effects in group sufentanil were superior to group fentanyl when patients were in the state of rest, coughing or moving respectively (P0.05). Less severe nausea and vomiting were recorded in group sufentanil. Analgesic drug consumption was comparable in two groups. Conclusion: Sufentanil with ropivacaine could be safe in PCEA after abdominal surgery. Sufentanil had better analgesic effect than fentanyl, with less side effects.

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Objective: To observe the analgesic and side effects of sufentanil or fentanyl combined with ropivacaine in postoperative patients with controlled epidural analgesia (PCEA). Methods:100 patients,ASA I~II,under going abdominal operation, were randomly divided into two groups. Sufentanil 0.5μg/ml or fentanyl 2 μg/ml with 0.12% ropivacaine were given epidurally after surgery, respectively, with basal dose of 4 ml/h, PCA dose of 2ml and lockout time of 20 min. Postoperative analgesic effects, PCEA pump usage,drug comsumption and side effects were observed within 48 hr. Results: Analgesic effects in group sufentanil were superior to group fentanyl when patients were in the state of rest, coughing or moving respectively (P0.05). Less severe nausea and vomiting were recorded in group sufentanil. Analgesic drug consumption was comparable in two groups. Conclusion: Sufentanil with ropivacaine could be safe in PCEA after abdominal surgery. Sufentanil had better analgesic effect than fentanyl, with less side effects.

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Available abstract

Objective: To observe the analgesic and side effects of sufentanil or fentanyl combined with ropivacaine in postoperative patients with controlled epidural analgesia (PCEA). Methods:100 patients,ASA I~II,under going abdominal operation, were randomly divided into two groups. Sufentanil 0.5μg/ml or fentanyl 2 μg/ml with 0.12% ropivacaine were given epidurally after surgery, respectively, with basal dose of 4 ml/h, PCA dose of 2ml and lockout time of 20 min. Postoperative analgesic effects, PCEA pump usage,drug comsumption and side effects were observed within 48 hr. Results: Analgesic effects in group sufentanil were superior to group fentanyl when patients were in the state of rest, coughing or moving respectively (P0.05). Less severe nausea and vomiting were recorded in group sufentanil. Analgesic drug consumption was comparable in two groups. Conclusion: Sufentanil with ropivacaine could be safe in PCEA after abdominal surgery. Sufentanil had better analgesic effect than fentanyl, with less side effects.

Key concepts: Sufentanil, Ropivacaine, Medicine, Fentanyl, Anesthesia, Nausea, Analgesic, Vomiting

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