Analysis of the Bacteria Spectrum Characteristics and Drug Resistance of Bacteria Isolated from Blood Culture

Objective To understand the bacteria spectrum characteristics and drug resistance of bacteria isolated from blood culture so as to guide the clinical rational administration. Methods Automated blood culture system Bact/Alert120 and special blood culture bottle were used to culture the bacteria, and the positive specimens were subcultivated to culture media for isolation, identification and drug sensitivity. Results A total of 291 strains of bacteria were isolated from 2370 blood culture specimens, the positive rate was 12.28%. Of the isolated 2 370 strains of bacteria clinically, gram positive bacteria accounted for 71%, gram negative bacteria accounted for 23%, fungi accounted for 1%, other bacteria accounted for 5%. The bacteria ranked the first three were coagulase negative staphylococcus(45%), Escherichia coli(26%), Staphylococcus aureus(13%). Most gram positive bacteria were high-ly sensitive to vancomycin, no drug-resistant strain occurred; most gram negative bacteria had lowest drug-resistant rate of imipenem, followed by amikacin. Conclusion The bacteria isolated from blood culture were mainly gram positive bacteria, coagulase negative staphylococcus has high proportion and antibiotic resistance rate. Understanding the distribution and drug resistance of bacte-ria in blood culture is of great importance in reducing bacterial resistance and nosocomial infection and guiding the rational drug use clinically.