Inhibitory Effect of Rubus delavayi Franch. on the Growth of Three Cancer Cell Lines in Vitro

[Objective] To study the effect of R.delavayi Franch.on three cancer cell lines in vitro.[Method] Human SGC7901,K562 and HL60 cells were treated with different concentrations of R.delavayi Franch.extracts in vitro.The growth inhibition ratio of the cells were analyzed by MTT assay.[Result] The chloroform extract and petroleum ether extract could inhibit the growth of SGC7901,K562 and HL60 cells.The higher the extracts concentration,the larger the inhibition ratio.The IC50 values of chloroform extracts against SGC7901 and K562 were 55.53 and 28.03 μg/ml.The IC50 values of petroleum ether extracts against SGC7901 and K562 were 29.52 and 14.99 μg/ml.But the IC50 values of the two extracts on HL60 were very large.The inhibition ratios of chloroform extracts and petroleum ether extracts were lower than that of 10 μg/ml cisplatin against three cancer cell lines.The ethyl acetate extracts,normal butanol extracts and water extracts hardly had inhibitory effects on three cancer cell lines.[Conclusion] The chloroform extracts and petroleum ether extracts of R.delavayi Franch.could inhibit the growth of SGC7901,K562 and HL60 cells in vitro.