2003•Shenyang Yaoke Daxue xuebaoRequires access

Simutaneous determination of the contents of rhein,emodin and chrysophanol in Weitongxin Granules by HPLC

Ying Jia

Abstract

Objective To develop a HPLC method for the determination of the contents of rhein,emodin and chrysophanol in the Weitonxin Granules.Methods The measurement conditions used were as follows: Accusil C 18( 4.6 mm× 250 mm)column; mobile phase: methanol-H 2O-acetic acid(80∶20∶1,V∶V∶V); flow rate: 1 mL/min; wavelength for rhein, emodin and chrysophanol showed good linear relation. The recovery rates for the rhein, emodin and chrysophanol were 98.3%(RSD=1.43%),97.6%(RSD=1.84%),98.7%(RSD=0.57%)respectively.The conditions of extraction and detemination were optimized.Conclusions The procedure is simple and rapid.The method can be used for evaluation of the crude drugs and their preparations.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Emodin, Chromatography, Chemistry, High-performance liquid chromatography, Acetic acid, Methanol, Biochemistry, Organic chemistry