Prognosis of coronary borderline lesion treated with percutaneous coronaryintervention in patients with coronary heart disease
Zhihua Deng
Abstract
Zhihua Deng
Abstract
Objective:To observe the prognosis of coronary borderline lesion treated with percutaneous coronary intervention(PCI) in patients with coronary heart disease except for myocardial infarction. Method:A total of 650 patients with coronary artery disease except for myocardial infarction were enrolled and divided into the MT group(n=448) in which patients were given optimal medicine therapy only and the PCI group(n=202) in which patients were treated with PCI as well as optimal medicine treatment.All the patients were followed up for 1 to 5 [average(3.95±1.24)] years to record the incidence of main cardiovascular adverse events(recurrent angina,arrhythmia,heart failure and target coronary revascularization) and long-time survival rate. Result:The patients in PCI group had higher incidences of recurrent angina,heart failure and target coronary revascularization than those in MT group(53.5% vs 33.7%,15.8% vs 9.2%,31.7% vs 11.8%,P=0.000,0.015 and 0.000,respectively).Keplan-Meier survival analysis showed that there were no significant differences in the long-time survival rate between the two groups. Conclusion:PCI increases the incidence of main cardiovascular adverse events and is not better than optimal medicine treatment in patients with borderline coronary lesion.
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Objective:To observe the prognosis of coronary borderline lesion treated with percutaneous coronary intervention(PCI) in patients with coronary heart disease except for myocardial infarction. Method:A total of 650 patients with coronary artery disease except for myocardial infarction were enrolled and divided into the MT group(n=448) in which patients were given optimal medicine therapy only and the PCI group(n=202) in which patients were treated with PCI as well as optimal medicine treatment.All the patients were followed up for 1 to 5 [average(3.95±1.24)] years to record the incidence of main cardiovascular adverse events(recurrent angina,arrhythmia,heart failure and target coronary revascularization) and long-time survival rate. Result:The patients in PCI group had higher incidences of recurrent angina,heart failure and target coronary revascularization than those in MT group(53.5% vs 33.7%,15.8% vs 9.2%,31.7% vs 11.8%,P=0.000,0.015 and 0.000,respectively).Keplan-Meier survival analysis showed that there were no significant differences in the long-time survival rate between the two groups. Conclusion:PCI increases the incidence of main cardiovascular adverse events and is not better than optimal medicine treatment in patients with borderline coronary lesion.
Key concepts: Medicine, Conventional PCI, Percutaneous coronary intervention, Internal medicine, Cardiology, Myocardial infarction, Coronary artery disease, Angina