2002•Unpublished venueRequires access
Study of 2-bromine-2-nitro-1,3-propanediol
Wei‐Guang Zhang
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Abstract
bromine-2-nitro-1,3-propanediol is synthesed from nitromethane and formaldehyde by hydroxyalkylation and bromination in the present of alkali.The effects of reation temperature,reaction time ,the volume ratio of water and alcohol in solvent and the amount of solvent on the yield of the product are investigated .The optimum conditions of the reaction are :volume ratio of water to alcohol is 0.4∶1.0,volume ratio of solvent to raw materials is 2.1∶1.0,reaction time of hydroxyalkylation is 1.5 hour at 5℃,reaction time of bromination is 0.5 hour at 10℃,the yield of the title compound is up to 78%.