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2008•Academic Journal of Guangzhou Medical CollegeRequires access

Effects of Electroacupuncture on Activity of GSH-Px and Serum Contents of GSH in Patients with Cerebral Infarction

Han Hui

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Abstract

Objective:To investigate the effects of electroacupuncture (EA) on activity of GSH-Px and serum contents of GSH in patients with cerebral infarction. Methods:Serum levels of GSH-Px and GSH in 20 patients with cerebral ischemia and 20 healthy controls were determined by colorimetry and compared between the two groups. Results:After treatment with electroacupuncture, the serum levels of GSH (11.95±1.67)mg/L and GSH-Px activity (192.49±19.27)IU in the ischemic patients were significantly increased as compared with baseline [(2.53±0.84)mg/L and (122.40±24.26)IU, P0.01] and with the control group [(4.98±0.83)mg/L and (144.06±35.07)IU, P0.01]. But GSH-Px activity and GSH content in serum in the pre-EA patients were found to be much lower than those in the control group (P0.01). Conclusion:EA was shown to increase the activities of anti-oxidants in human, which may be useful to scavenge free radicals generated from oxidative stress in patients with cerebral infarction.

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Objective:To investigate the effects of electroacupuncture (EA) on activity of GSH-Px and serum contents of GSH in patients with cerebral infarction. Methods:Serum levels of GSH-Px and GSH in 20 patients with cerebral ischemia and 20 healthy controls were determined by colorimetry and compared between the two groups. Results:After treatment with electroacupuncture, the serum levels of GSH (11.95±1.67)mg/L and GSH-Px activity (192.49±19.27)IU in the ischemic patients were significantly increased as compared with baseline [(2.53±0.84)mg/L and (122.40±24.26)IU, P0.01] and with the control group [(4.98±0.83)mg/L and (144.06±35.07)IU, P0.01]. But GSH-Px activity and GSH content in serum in the pre-EA patients were found to be much lower than those in the control group (P0.01). Conclusion:EA was shown to increase the activities of anti-oxidants in human, which may be useful to scavenge free radicals generated from oxidative stress in patients with cerebral infarction.

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Available abstract

Objective:To investigate the effects of electroacupuncture (EA) on activity of GSH-Px and serum contents of GSH in patients with cerebral infarction. Methods:Serum levels of GSH-Px and GSH in 20 patients with cerebral ischemia and 20 healthy controls were determined by colorimetry and compared between the two groups. Results:After treatment with electroacupuncture, the serum levels of GSH (11.95±1.67)mg/L and GSH-Px activity (192.49±19.27)IU in the ischemic patients were significantly increased as compared with baseline [(2.53±0.84)mg/L and (122.40±24.26)IU, P0.01] and with the control group [(4.98±0.83)mg/L and (144.06±35.07)IU, P0.01]. But GSH-Px activity and GSH content in serum in the pre-EA patients were found to be much lower than those in the control group (P0.01). Conclusion:EA was shown to increase the activities of anti-oxidants in human, which may be useful to scavenge free radicals generated from oxidative stress in patients with cerebral infarction.

Key concepts: Electroacupuncture, Glutathione, Cerebral infarction, Oxidative stress, Internal medicine, Medicine, Endocrinology, Ischemia

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Effects of Electroacupuncture on Activity of GSH-Px and Serum Contents of GSH in Patients with Cerebral Infarction — Research Paper | ScholarLens