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2013•Zhongguo shiyan fangjixue zazhiRequires access

Optimization of Ethanol Extraction Process for Sisheng Granules with Orthogonal Test

Songshan Liu

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Abstract

Objective:To optimize ethanol extraction process of Sisheng granules.Method:L9(34) orthogonal test was adopted to investigate effects of extraction time,the amount of ethanol and ethanol concentration on ethanol extraction process with composite score of yield of verbascoside,nuciferine and dry extract as index.Result:Optimal extraction conditions were as follows:reflux extracted 2 times with 12 folds the amount of 60% ethanol,1 h per time.Conclusion:Optimized ethanol extraction process was stable and feasible,it could be extended for application in industrial production.

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Objective:To optimize ethanol extraction process of Sisheng granules.Method:L9(34) orthogonal test was adopted to investigate effects of extraction time,the amount of ethanol and ethanol concentration on ethanol extraction process with composite score of yield of verbascoside,nuciferine and dry extract as index.Result:Optimal extraction conditions were as follows:reflux extracted 2 times with 12 folds the amount of 60% ethanol,1 h per time.Conclusion:Optimized ethanol extraction process was stable and feasible,it could be extended for application in industrial production.

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Available abstract

Objective:To optimize ethanol extraction process of Sisheng granules.Method:L9(34) orthogonal test was adopted to investigate effects of extraction time,the amount of ethanol and ethanol concentration on ethanol extraction process with composite score of yield of verbascoside,nuciferine and dry extract as index.Result:Optimal extraction conditions were as follows:reflux extracted 2 times with 12 folds the amount of 60% ethanol,1 h per time.Conclusion:Optimized ethanol extraction process was stable and feasible,it could be extended for application in industrial production.

Key concepts: Extraction (chemistry), Ethanol, Chromatography, Yield (engineering), Process (computing), Chemistry, Materials science, Computer science

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