2005•Xinjiang Yike Daxue xuebaoRequires access

The establishment of orthotopic liver transplantation in rat

Ming Lü

Abstract

Objective: To make an ideal model for liver transplantation. Methods: Two Cuff (portal vein and infrahepatic vena cava) technique was applied in the production of this animal model in Wistar rats and SD rats. Results: With the modifiation, a successful rate of 83.3% was achieved in the production of the experimental model with anhepatic period of on average 19 minutes. Conclusion: The results show that the model is easily available and highly reproducible and can be used in the experiment of liver transplantation.

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Available abstract

Key concepts: Portal vein, Liver transplantation, Orthotopic liver transplantation, Medicine, Transplantation, Cuff, Animal model, Vena cava