Clinical study on effect of sequential colon dialysis in patients with chronic renal failure in early and medium stage

Objective: To observe the effect of sequential colon dialysis in patients with chronic renal failure(CRF) in early and medium stage.Methods: One hundred and forty-two CRF patients in early and medium stage were treated with sequential colon dialysis and traditional Chinese medicine according to(traditional) Chinese medical syndrome differentiation and typing,and clinical syndromes were observed.(Sixty-three) patients with CRF were selected as controls treated with low protein diet plus essential amino acids.The serum levels of blood urea nitrogen(BUN),creatinine(Cr),uric acid(UA),the creatinine(clearance) rate(CCr),electrolyte and medium molecular substance(MMS) were measured before and after treatment.Results: The clinical symptoms of the 142 patients were improved,the serum levels of BUN,Cr,UA and MMS were decreased significantly(BUN:(15.3±4.5)mmol/L vs.(8.6±3.3)mmol/L;Cr:((443.6±73.5)μmol/L) vs.(283.5±38.7) μmol/L;UA:(512.6±86.5)μmol/L vs.(243.1±33.6)μmol/L;MMS: 0.44±0.06 vs.0.32±0.04),and CCr increased markedly((9.87±3.31)ml/min vs.(15.60±(4.63)ml/min)).The difference between treatment group and control group was significant.The changes in electrolyte levels were not significant before and after treatment in both groups.Conclusion: Sequential colon dialysis has obviously curative effects on CRF patients in early and medium stage,and could ameliorate the(develope) of CRF in early and medium stage.