Study on Optimization of Technology for Extracting Perilla Oil by Supercritical CO_2 Extraction

[Objective] The propose of study was to optimize the technology for extracting perilla oil by supercritical CO2 extraction and provide the scientific basis for the development of the resources of perilla.[Method] The supercritical CO2 fluid was used as the extraction solvent to extract the perilla oil from the drug material of perilla seed.With the oil yielding rate of the extracted perilla seed as the index,the optimum technology for extracting perilla seed oil by supercritical CO2 extraction through L9(33)orthogonal test was screened and the effects of 3 factors including extraction temperature,extraction pressure,and CO2 dynamic flow on the yield of perilla seed oil extraction were studied.[Result] The optimum technology for extracting perilla seed oil by supercritical CO2 extraction was the extraction pressure of 20 MPa,extraction temperature of 40 ℃ and CO2 dynamic flow of 30 L/h.Among the 3 influence factors,the effect of the extraction pressure was most significant,that of CO2 dynamic flow was next and that of extraction temperature was lowest.[Conclusion] Using supercritical CO2 extraction technique to extract the liposoluble constituents had the characters of quick speed,high efficiency and no pollution,with the cyclic utilization of menstruum CO2,so it is highly feasible to extract the perilla oil by supercritical CO2 extraction.