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2011•Medical Journal of West ChinaRequires access

Clinical observation on low dose thalidomide combined with the dexamethasone in treatment of multiple myeloma

Qi He

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Abstract

Objective To observe the effect of thalidomide in low dose combined with dexamethasone in treatment of multiple myeloma(MM).Methods the dose of thalidomide was gradually increased form 100mg/d to 200mg/dDexamethasone was given for 15mg/d,1-4days once a month.Results 4 of 16 cases with MM partially released,9 cases improved,and 3 cases was ineffective.The total effective rate was 81.2%(13/16).There were no side effects not to be tolerated.Conclusion.Conciusion Combination of the thalidomide in low dose with dexamethasone on treatment of multiple myeloma shows obvious effects.

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What this paper is about

Objective To observe the effect of thalidomide in low dose combined with dexamethasone in treatment of multiple myeloma(MM).Methods the dose of thalidomide was gradually increased form 100mg/d to 200mg/dDexamethasone was given for 15mg/d,1-4days once a month.Results 4 of 16 cases with MM partially released,9 cases improved,and 3 cases was ineffective.The total effective rate was 81.2%(13/16).There were no side effects not to be tolerated.Conclusion.Conciusion Combination of the thalidomide in low dose with dexamethasone on treatment of multiple myeloma shows obvious effects.

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Available abstract

Objective To observe the effect of thalidomide in low dose combined with dexamethasone in treatment of multiple myeloma(MM).Methods the dose of thalidomide was gradually increased form 100mg/d to 200mg/dDexamethasone was given for 15mg/d,1-4days once a month.Results 4 of 16 cases with MM partially released,9 cases improved,and 3 cases was ineffective.The total effective rate was 81.2%(13/16).There were no side effects not to be tolerated.Conclusion.Conciusion Combination of the thalidomide in low dose with dexamethasone on treatment of multiple myeloma shows obvious effects.

Key concepts: Thalidomide, Medicine, Dexamethasone, Multiple myeloma, Internal medicine

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