A clinical evaluation of sodium hyaluronate in treating adhesive intestinal obstruction

Objective To observe the clinical effect of sodium hyaluronate on treating adhesive intestinal obstruction. Methods Thirty patients with adhesive intestinal obstruction were performed with surgical separation of adhesion. 10 ml medical sodium hyaluronate (Sofast) was diluted in 100 ml of normal saline and detained in intestinal canal. 3 - 5 ml of sodium hyaluronate (Sofast) was sprayed on the lesions of intestine and peritoneum. Results All patients lived through perioperative period and postoperative timing of exhaust was medially 36.8 hours. No symptoms of intestinal obstruction occurred postoperatively. After following up for mean 525 days, 1 case was reoper-ated at the 156th days postoperatively; 2 cases were conservatively treated again at the 121st and 68th days; 2 cases caught bellyache occasionally, but did nothing because of no sign of intestinal obstruction. Others disappeared intestinal obstruction symptoms during the follow-up period. Conclusions Sodium hyaluronate is effective and safe in the treatment of adhesive intestinal obstruction.