Study on the Performance of Hydroxypropyl Methyl Cellulose and Starch Ether Blending System

It prepared the high viscosity of hydroxypropyl methyl cellulose(HPMC) and hydroxypropyl starch(HPS) blends with different blending ratio of HPMC and HPS,and the viscosity and rheological change rule were studied by using the NDJ-1 type of rotating viscometer and Anton Paar Physica MCR 301 type of rheometry,the light transmittance and the water retention rate change rule were also studied.Results showed that with the HPS content heighten,the viscosity and light transmittance of blends with samples gradually reduced,but the viscosity was more stable in larger shear rate scope and the solution showed good shear performance.The water retention rate of blends with sample was significantly higher than single HPMC products when HPS was blended in,and with the HPS content heighten,the water retention rate slowly reduced after a first significant rise,and then slowly increased.Reasonable choice of HPMC viscosity and the mixture,and according to the viscosity of HPMC,a certain proportion of blends with could low cost satisfy the medicine capsule application requirements.