Analysis of Correlation between Pathologic Changes and HP Infection in Gastric Cancer

Objective: To explore the HP infection and gastric cancer patients with pathologic correlation characteristic change.Methods: To choose our digestive internal medicine and 50 cases of patients diagnosed with cancer of the stomach as gastric cancer group, 50 cases with chronic superficial gastritis as gastritis group, and 50 cases of patients, who were found with no abnormalities in stomach in physical examination during the same period, as control group. Urea nitrogen of the three groups of patients at high speed test,13 curea breath test and serum anti HPCag A check, more patients with HP infection. Results: Patients with gastric cancer and gastritis positive rate of HP infection and anti HPCag A positive rate was significantly higher, and gastric cancer was significantly higher than the gastritis group, the difference was statistically significant(P 0.05). Early and advanced gastric cancer patients with HP infection rate higher, and the difference was statistically significant(P 0.05). Non-cardia gastric cancer patients HP infection rate was significantly higher than the cardia and control group, the difference was statistically significant(P 0.05). Conclusion: HP infection is the leading cause of cancer of the stomach pathogenic factors, clear HP infection and gastric cancer pathological staging and the correlation of the lesion site, which is important for prevention and treatment of gastric cancer in clinical practice.