Value of combined detection of seminal plasma biochemistry and spermatogenic cells in azoospermia analysis

Objective To explore the value of combined detection of seminal plasma biochemistry and spermatogenic cells in azoospermia analysis.Methods Plasma biochemical determination standard for routine analysis of semen and sperm bank on the semen of 74cases with azoospermia,spermatogenic cells were detected by the papanicolaoumethod.According to the semen volume,pH value,the content of fructose,neutralα-glycosylase activity and spermatogenic cells,the causes of azoopermism were typed and compared to the findings from testicular biopsy.Results Of 74azoopermia patients,68 cases(91.9%)were definitely diagnosed,of whom 40(54.1%)cases were obstructive azoopermia.Fourteen cases(18.9%)were absence of deferens or ejaculatory duct obstruction,5cases(6.8%)were deferens obstruction or epididymal obstruction,21cases(28.4%)were epididymis head obstruction,28 cases(37.8%)were epididymal sperm atogenicdysfuntion.The positive rate of testicular biopsy of obstructive azoospermia group was higher than that of nonobstructive group(P0.01).Conclusion The combined detection of seminal plasma biochemistry and spermatogenic cell is valuable for differentiating the obstructive and nonobstructive azoospermia and deciding the location of the obstruction.