Comparison of result of sleep monitoring between patients with narcolepsy and patients with obstructive sleep apnea-hypopnea syndrome

Objective To explore the characteristics of the sleep monitoring in patients with narcolepsy and patients with obstructive sleep apnea-hypopnea syndrome( OSAHS). Methods The sleep latency( SL),sleep onset rapid eye movement period( SOREMP),total sleep times( TST),sleep efficiency( SE) and apnea hypopnea index( AHI) were determined in 15 patients with narcolepsy group and 15 patients with OSAHS group using multiple sleep latency test( MSLT) and all-night sleep recording by polysomnography( PSG) measurements,and the monitoring results were compared between two groups. Results Compared to OSAHS group,narcolepsy group showed SL was shorter significantly[( 3. 93 ± 2. 99) min vs( 10. 39 ± 2. 01) min,P 0. 01]and SOREMP was increased significantly [( 2. 87 ±0. 83) vs( 0. 27 ± 0. 59) times/h,P 0. 01]on MSLT. The sleep parameters of PSG showed that compared to OSAHS group,TST was less[( 395. 77 ± 47. 74) min vs( 495. 95 ± 29. 15) min,P 0. 01],and SE was lower [( 75. 95 ±4. 37) % vs( 82. 81 ±2. 81) %,P 0. 01]in the narcolepsy group than those in the OSAHS group( P 0. 01); AHI was higher in OSAHS group than that in narcolepsy[( 25. 85 ± 3. 61) vs( 0. 79 ± 1. 08) times / h,P 0. 01]. Conclusion SL was shorter and SOREMP was more in narcolepsy group than those in OSAHS group. PSG showed that TST was less,and SE was lower in narcolepsy group than those in OSAHS group. The sleep respiratory disturbance is more obvious in the OSAHS group than that in narcolepsy group. The MSLT combined with PSG have played an important role in the diagnosis and differential diagnosis of narcolepsy and OSAHS.