Magnetic resonance spectroscopy study on the edema post cerebral hemorrhage and correlating factors

Objective To observe the MR spectroscopy(MRS) characteristic of the delayed edema post cerebral hemorrhage and analysis of correlation factors.Methods Twelve cases of edema post cerebral hemorrhage after 7 and 14 days were performed with MRS study around the edema area and 7 days' edema were examined as control group.Quantitative analysis NAA change and lactic acid peak and mannitol peak.Results 9 patients obtain satisfaction MRS,Compared with the 7 days' MRS,the NAA/Cr decreased(15.7%±9.2%)(P0.01) in the delayed edema area,The lactic acid peaks were observed in 7 cases and the mannitol peak in 8 cases.Conclusion The NAA/Cr reduced and the lactic acid peak appeared in the delayed edema area may support neuron's damage and ischemia,And mannitol peak's existence,had played an important role to the delayed edema,prompted the destruction of the partial blood brain barrier.