2006Guoji shengwu yixue gongcheng zazhiRequires access

Progress of mesenchymal stem cells in umbilical cord blood

Zuo-Hua Chi, Yuan Zhang

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Abstract

There are plenty of haematopoietic stem cells in umbilical cord blood, which are regarded as important resources for transplantation therapy. There are some arguments on whether or not mesenchymal stem cells(MSCs) exist in umbilical cord blood. Some researchers have such opinions that there exist a number of MSCs in umbilical cord blood as similar with one from bone marrow in many aspects. Others believe that the content of MSCs in umbilical cord blood is too low to expand in vitro. We summarized the data from last five years researches. On umbilical cord blood MSCs during last to help further research and application of this resource of MSCs.

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What this paper is about

There are plenty of haematopoietic stem cells in umbilical cord blood, which are regarded as important resources for transplantation therapy. There are some arguments on whether or not mesenchymal stem cells(MSCs) exist in umbilical cord blood. Some researchers have such opinions that there exist a number of MSCs in umbilical cord blood as similar with one from bone marrow in many aspects. Others believe that the content of MSCs in umbilical cord blood is too low to expand in vitro. We summarized the data from last five years researches. On umbilical cord blood MSCs during last to help further research and application of this resource of MSCs.

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Available abstract

There are plenty of haematopoietic stem cells in umbilical cord blood, which are regarded as important resources for transplantation therapy. There are some arguments on whether or not mesenchymal stem cells(MSCs) exist in umbilical cord blood. Some researchers have such opinions that there exist a number of MSCs in umbilical cord blood as similar with one from bone marrow in many aspects. Others believe that the content of MSCs in umbilical cord blood is too low to expand in vitro. We summarized the data from last five years researches. On umbilical cord blood MSCs during last to help further research and application of this resource of MSCs.

Key concepts: Umbilical cord, Cord lining, Mesenchymal stem cell, Haematopoiesis, Stem cell, Medicine, Cord blood, Bone marrow

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