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2007•Yixue fenzi shengwuxue zazhiRequires access

CCL25 and CCL28 and Their Cognate Receptors CCR9 and CCR10

Xin Qiao

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Abstract

CCL25 and CCL28,members of chemokine CC subfamily,are primarily expressed in thymic dendritic cells and mucosal epithelial cells.The cognate receptors of CCL25 and CCL28 are CCR9 and CCR10 expressed in T and B lymphocytes.CCL25 and CCL28,with their cognate receptors,play essential roles in homing of circulating IgA secreting cells and T lymphocytes,and CCL28 also has a broad-spectrum antimicrobial activity.

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What this paper is about

CCL25 and CCL28,members of chemokine CC subfamily,are primarily expressed in thymic dendritic cells and mucosal epithelial cells.The cognate receptors of CCL25 and CCL28 are CCR9 and CCR10 expressed in T and B lymphocytes.CCL25 and CCL28,with their cognate receptors,play essential roles in homing of circulating IgA secreting cells and T lymphocytes,and CCL28 also has a broad-spectrum antimicrobial activity.

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Available abstract

CCL25 and CCL28,members of chemokine CC subfamily,are primarily expressed in thymic dendritic cells and mucosal epithelial cells.The cognate receptors of CCL25 and CCL28 are CCR9 and CCR10 expressed in T and B lymphocytes.CCL25 and CCL28,with their cognate receptors,play essential roles in homing of circulating IgA secreting cells and T lymphocytes,and CCL28 also has a broad-spectrum antimicrobial activity.

Key concepts: CCL25, CC chemokine receptors, CCR10, Chemokine receptor, Receptor, Biology, Chemokine, Cell biology

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