[Effects of high volume hemofiltration on postoperative multiple organ dysfunction syndrome in severe abdominal infection patients].

AIM: To evaluate the clinical efficacy of high-volume hemofiltration (HVHF) on treating postoperative multiple organ dysfunction syndrome in severe abdominal infection patients. METHODS: Data of 17 severe abdominal infection patients treated with HVHF were collected and the differences on oxygenation indices, APACHE-II scores before and after HVHF therapy were observed. RESULTS: After the first HVHF treatment, the oxygenation index improved, and the APACHE-II scores, TNF-alpha, IL-6, and IL-8 decreased significantly (P<0.05). After several HVHF treatments, the oxygenation index improved, and the APACHE-II scores decreased significantly (P<0.05). CONCLUSION: HVHF can improve both the respiratory function and vital signs of severe sepsis patients and relieve the severity of the illness.