2010Zhongguo shiyan fangjixue zazhiRequires access

Studies on Chemical constituents of Mosla chinensis 'jiangxiangru'

Liu Hua, Dongming Zhang

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Abstract

Objective:To study chemical constituents of Mosla chinensis'jiangxiangru'.Method:Silica gel column chromatography,Sephadex LH-20 gel column chromatography and MPLC were employed for the isolation and purification.The structures were identified on the basis of spectral data and chemical methods.Result:Twelve compounds were identified as follows:β-D-Glucopyranosyl indole-3-carboxylic acid(1),carvacrol(2),thymoquinol-2-O-β-glucopyranoside(3),thymoquinol-5-O-β-glucopyranoside(4),thymoquinol-2,5-O-β-diglucopyranoside(5),luteolin(6),negletein(7),syringic acid(8),p-hydroxybenzoic acid(9),dibutyl terephthalte(10),oleanolic acid(11),β-sitosterol(12).Conclusion:these compounds were isolated for the first time from Mosla chinensis 'jiangxiangru'.Among them,3-carboxyindole-β-glucopyranosid,thymoquinol-2-O-β-glucopyranoside,thymoquinol-5-O-β-glucopyranoside,thymoquinol-2,5-O-β-diglucopyranoside have not been previously described in genus Mosla.

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What this paper is about

Objective:To study chemical constituents of Mosla chinensis'jiangxiangru'.Method:Silica gel column chromatography,Sephadex LH-20 gel column chromatography and MPLC were employed for the isolation and purification.The structures were identified on the basis of spectral data and chemical methods.Result:Twelve compounds were identified as follows:β-D-Glucopyranosyl indole-3-carboxylic acid(1),carvacrol(2),thymoquinol-2-O-β-glucopyranoside(3),thymoquinol-5-O-β-glucopyranoside(4),thymoquinol-2,5-O-β-diglucopyranoside(5),luteolin(6),negletein(7),syringic acid(8),p-hydroxybenzoic acid(9),dibutyl terephthalte(10),oleanolic acid(11),β-sitosterol(12).Conclusion:these compounds were isolated for the first time from Mosla chinensis 'jiangxiangru'.Among them,3-carboxyindole-β-glucopyranosid,thymoquinol-2-O-β-glucopyranoside,thymoquinol-5-O-β-glucopyranoside,thymoquinol-2,5-O-β-diglucopyranoside have not been previously described in genus Mosla.

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Available abstract

Objective:To study chemical constituents of Mosla chinensis'jiangxiangru'.Method:Silica gel column chromatography,Sephadex LH-20 gel column chromatography and MPLC were employed for the isolation and purification.The structures were identified on the basis of spectral data and chemical methods.Result:Twelve compounds were identified as follows:β-D-Glucopyranosyl indole-3-carboxylic acid(1),carvacrol(2),thymoquinol-2-O-β-glucopyranoside(3),thymoquinol-5-O-β-glucopyranoside(4),thymoquinol-2,5-O-β-diglucopyranoside(5),luteolin(6),negletein(7),syringic acid(8),p-hydroxybenzoic acid(9),dibutyl terephthalte(10),oleanolic acid(11),β-sitosterol(12).Conclusion:these compounds were isolated for the first time from Mosla chinensis 'jiangxiangru'.Among them,3-carboxyindole-β-glucopyranosid,thymoquinol-2-O-β-glucopyranoside,thymoquinol-5-O-β-glucopyranoside,thymoquinol-2,5-O-β-diglucopyranoside have not been previously described in genus Mosla.

Key concepts: Chemistry, Syringic acid, Oleanolic acid, Silica gel, Column chromatography, Sephadex, Chromatography, Luteolin

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