Analysis on risk factors for intracranial infection after intracranial tumor operation

Objective To investigate the risk factors and preventive measures for intracranial infection after excision of intracranial tumor.Methods Clinical data of 442 patients with excision of intracranial tumor were reviewed.Results Thirty-three of 442 patients occurred intracranial infection,infection rate was(7.47%),the infection rate of non-meningoma operation was(10.04%),which was higher than that of meningoma operation((3.83%))(P(0.05));The infection rate in patients with operation time ≥4 hours was(9.87%),which was higher than that of 4 hours((4.78%))(P(0.05));The infection rate in patients with leakage of cerebrospinal fluid and without leakage of cerebrospinal fluid was(15.00%) and(6.28%) respectively(P(0.05));The infection rate in patients with drainage tube duration ≥24 hours and 24 hours was(11.58%) and(5.03%) respectively(P(0.05)).Conclusion The main risk factors for post-operative intracranial infection in patients with excision of intracranial tumor were operation time ≥4 hours,drainage tube duration ≥24 and leakage of cerebrospinal fluid.