2011•Biaoji mianyi fenxi yu linchuangRequires access
Application of RPR,TP-ELISA and TPPA in Syphilis Screening in Voluntary Blood Donors
Gao Su-ping
Open publisher page 0 citations
Abstract
To explore the application values of RPR,TP-ELISA and TPPA in syphilis screening in voluntary blood donors,and to choose a suitable model for screening syphilis in blood center.RPR and TP-ELISA were used to screen samples of 20200 blood donors for treponema pallidum(TP) infection and these positive samples were tested by TPPA.The results showed that the positive rates of RPR and TP-ELISA were 0.45% and 0.77%,respectively.There was significant difference between RPR and TP-ELISA(P0.01).There were 61 and 137 positive samples screened by TPPA,and the coincidences between TPPA with RPR and TP-ELISA were 67.0% and 88.4%,respectively.The study indicates that TP-ELISA is the optimal method in detecting syphilis for massive screening of blood donors.