Detection and drug resistance analysis of genitourinary tract mycoplasma in Chaozhou area

Objective To study the infection situation of genitourinary tract mycoplasma and their drug resistance in Chaozhou region, and to help doctors to select reasonable application of antibiotics. Methods Ureaplasma urealyticum (Uu) and human mycoplasma hominis (Mh) were isolated, and their antibiotic susceptibility were detected with Mycoplasma IST 2 Reagent BOX from France in 2725 cases of genitourinary tract suspected infection patient specimens. Results Among 2725 cases of suspected specimens, 1343 cases were positive for mycoplasma, accounting for 49.3% of the total specimens. Among them, the positive rate of Uu, Mh and mixed infection of Uu and Mh were 27.9% (759 cases), 2.9% (79 cases), and 18.5% (505 cases) respectively. Mycoplasma infection in female patient specimens were significantly higher than those in male patients. Susceptibility test results showed that quinolone antibiotic resistance rates was highest for mycoplasma, pristinamycin resistance rate was lowest, and the tetracycline antibiotics resistance rates was also lower. 9 kinds of antimicrobial drug resistance rate for Uu and Mh mixed infection were higher than that of single Uu infection. Conclusion For the treatment experiential of mycoplasma infection in Chaozhou region, the first candidate antibiotics was pristinamycin, followed by josamycin and tetracycline, and appropriate antibiotics selection should be based on the antimicrobial drug susceptibility results of laboratory.