Association between metabolic syndrome and carotid atherosclerosis in T2DM

Objective To investigate the association and significance between metabolic syndrome(MS) and carotid atherosclemsis in T2DM.Methods According to the definition of MS by CDS in 2004,220 subjects were enrolled and divided into three groups including MS group with between 3 to 4 components(n=104),MS subgroup with between 1 to 2 components(n=56),and controll group(n=60).Carotid intima-media thickness(IMT) was detected.Compare the carotid atherosclerosis in the three groups.Results The IMT was higher in MS group and in MS subgroup compared with control group.CCA-IMT was positively corelate with body mass index,systolic blood pressure and diastolic blood pressure significantly.Conclusion The MS accelerated the occurrence and progress of carotid athemsclerosis.Clustering of multiple components may cause more severe carotid atherosclerosis in MS.Carotid ultrasound may help diagnosis atherosclemsis much earlier.