The Effect of Sequential Invasive to Noninvasive Mechanical Ventilation in Severe Respiratory Failure

Objective: To explore the clinical therapeutic effect and feasibility of sequential invasive to noninvasive mechanical ventilation in severe respiratory failure. Method: Treatment group was 35 patients with severe respiratory failure underwent sequential invasive and noninvasive mechanical ventilation at the switch-point of respiratory pump failure improved,control group was 35 patients with underwent conventional treatment,and analysed and compared the total mechanical ventilation time,pressure invasive mechanical ventilation time,incidence rate of repeated tracheal intubation,the incidence rate of ventilator associated pneumonia( VAP) and total length of stay. Result: Sequential invasive and noninvasive mechanical ventilation in severe respiratory failure had significant therapeutic effect.There was no significant difference of APACHEⅡ score between the two groups.The total mechanical ventilation time,pressure invasive mechanical ventilation time,total length of stay and the incidence rate of VAP in treatment group were lower than control group( P0.05). Conclusion: Sequential invasive and noninvasive mechanical ventilation at the switchpoint of respiratory pump failure improved can reduce total mechanical ventilation time,the pressure invasive mechanical ventilation time and total length of stay. It can reduce the incidence rate of VAP.