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2007•Chinese Journal of Laboratory DiagnosisRequires access

The Effect of Interleukin-6 in Diagnosis and Prognosis of Ovarian Carcinoma

Yingjian Chen

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Abstract

Objective To explore the effect of Interleukin-6 in diagnosis and prognosis of ovarian carcinoma.Methods 54 cases with ovarian carcinoma as study group,which 15 cases in Ⅰ-Ⅱ stage and 39 cases in Ⅲ stage,and 22 cases with ovarian benign and 18 normal women as control groups.All cases were selected from First Hospital of Medical College of Shantou University from 2004-1 to 2006-12.The levels of IL-6 in serum were measured by enzyme-labeled immunosorbent assay(ELISA).Results ①The levels of IL-6 in serum in study group were significantly higher than those in controls group(P0.05).②In study group,the levels of IL-6 in serum in Ⅲ stage were significantly higher than that in Ⅰ-Ⅱstages(P0.05).③The levels of IL-6 in serum were significantly lower after chemical therapy.Conclusion IL-6 has much valuable in diagnosis of ovarian carcinoma,and also in determines of clinic stage.But IL-6 was not as a tumor marker of to decide the effect of chemical therapy.

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Objective To explore the effect of Interleukin-6 in diagnosis and prognosis of ovarian carcinoma.Methods 54 cases with ovarian carcinoma as study group,which 15 cases in Ⅰ-Ⅱ stage and 39 cases in Ⅲ stage,and 22 cases with ovarian benign and 18 normal women as control groups.All cases were selected from First Hospital of Medical College of Shantou University from 2004-1 to 2006-12.The levels of IL-6 in serum were measured by enzyme-labeled immunosorbent assay(ELISA).Results ①The levels of IL-6 in serum in study group were significantly higher than those in controls group(P0.05).②In study group,the levels of IL-6 in serum in Ⅲ stage were significantly higher than that in Ⅰ-Ⅱstages(P0.05).③The levels of IL-6 in serum were significantly lower after chemical therapy.Conclusion IL-6 has much valuable in diagnosis of ovarian carcinoma,and also in determines of clinic stage.But IL-6 was not as a tumor marker of to decide the effect of chemical therapy.

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Available abstract

Objective To explore the effect of Interleukin-6 in diagnosis and prognosis of ovarian carcinoma.Methods 54 cases with ovarian carcinoma as study group,which 15 cases in Ⅰ-Ⅱ stage and 39 cases in Ⅲ stage,and 22 cases with ovarian benign and 18 normal women as control groups.All cases were selected from First Hospital of Medical College of Shantou University from 2004-1 to 2006-12.The levels of IL-6 in serum were measured by enzyme-labeled immunosorbent assay(ELISA).Results ①The levels of IL-6 in serum in study group were significantly higher than those in controls group(P0.05).②In study group,the levels of IL-6 in serum in Ⅲ stage were significantly higher than that in Ⅰ-Ⅱstages(P0.05).③The levels of IL-6 in serum were significantly lower after chemical therapy.Conclusion IL-6 has much valuable in diagnosis of ovarian carcinoma,and also in determines of clinic stage.But IL-6 was not as a tumor marker of to decide the effect of chemical therapy.

Key concepts: Ovarian carcinoma, Stage (stratigraphy), Medicine, Internal medicine, Gastroenterology, Carcinoma, Interleukin 1β, Oncology

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