The comparative study on the results of serum enzymes between Hitachi 7170A and COBAS Integra 400 plus

Objective:To study the comparability on the results of serum enzymes between Hitachi 7170A and COBAS Integra 400 plus.Methods:With the Hitachi7170A biochemical analyzers,Roche reagent and program,Roche c-fas calibration as a target system,COBAS Integra 400 plus as comment system.The AST?LDH?CK?CK-MB were analysed in 41?32?32?30 patient fresh sera respectively and 2 levels of Roche controls.It was judgement whether the results on different analysis systems were comparability according to the half of CLIA,88 with calculation the system bias between target system and comment system.Results:Analysis of variance showed the results of patient sera enzymes had no significant difference between two detection system,and also the correlation coefficient was all above 0.975.The system errors on the all results between Hitachi 7170A and COBAS Integra 400 plus were clinical acceptable.Conclusion:The results of AST?LDH?CK?CK-MB between two analysis systems were comparable,and able to satisfy clinical need.