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2003•Bulletin of Chinese CancerRequires access

The Clinicopathological Features and Immunohistochemical Study of Primary Lymphoma of Central Nervous System

Gu Zhang

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Abstract

To investigate the clinicopathological features of primary central nervous sys-tem lymphoma(PCNSL).Data of10cases with PCNSL were collected,and pathological morphology and immunohistochemical results were analysed.The pathological morpholo-gy and immunohistochemical results showed that all the10cases were B-cell lymphoma.Among them,8cases were diffuse large B-cell lymphoma,2cases were B-small type.[Conclusions]The PCNSL is rare and highly malignant tumor in the brain.The majority of PCNSL were derived from B cells.The tumor cells surround and involve vessels forming cuffing.Immunohistochemistry plays an important role in diagnosis of PCNSL.

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What this paper is about

To investigate the clinicopathological features of primary central nervous sys-tem lymphoma(PCNSL).Data of10cases with PCNSL were collected,and pathological morphology and immunohistochemical results were analysed.The pathological morpholo-gy and immunohistochemical results showed that all the10cases were B-cell lymphoma.Among them,8cases were diffuse large B-cell lymphoma,2cases were B-small type.[Conclusions]The PCNSL is rare and highly malignant tumor in the brain.The majority of PCNSL were derived from B cells.The tumor cells surround and involve vessels forming cuffing.Immunohistochemistry plays an important role in diagnosis of PCNSL.

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Available abstract

To investigate the clinicopathological features of primary central nervous sys-tem lymphoma(PCNSL).Data of10cases with PCNSL were collected,and pathological morphology and immunohistochemical results were analysed.The pathological morpholo-gy and immunohistochemical results showed that all the10cases were B-cell lymphoma.Among them,8cases were diffuse large B-cell lymphoma,2cases were B-small type.[Conclusions]The PCNSL is rare and highly malignant tumor in the brain.The majority of PCNSL were derived from B cells.The tumor cells surround and involve vessels forming cuffing.Immunohistochemistry plays an important role in diagnosis of PCNSL.

Key concepts: Immunohistochemistry, Primary central nervous system lymphoma, Lymphoma, Pathology, Pathological, Central nervous system, Medicine, Internal medicine

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