Synthesis of 4-Methoxy-dibenzoyl methane with Microwave Irradiation

Microwave irradiation was used for the preparation of 4-methoxy-dibenzoyl methane from p-methoxy acetophenone and benzoate.The optimum conditions were found as follows:the molar ratio of p-methoxy acetophenone,ethyl benzoate and NaNH2 was 1:15:4,the power of microwave irradiation was 320 W and the reaction time was 45 min.The yield of the target compound was 77.4%.In comparison,the traditional method gives only 61.4% yield in much longer reaction time of 7 h.The product structure was confirmed by means of elemental analysis,IR and 1H NMR.