Study on the relationship between cerebral micorbleeds and severity of hypertension assessed by ssceptibilityweighted imaging

Objective To explore the diagnosis value of susceptibility-weighted imaging( SWI) for cerebral micorbleeds( CMBs),and study the relationship between cerebral micorbleeds and severity of hypertension assessed by SWI,in order to provides the reference for clinician. Methods Clinical data on routine MRI and SWI of 150 patients with hypertension combined with CMBs in the department of neurology in our hospital was retrospectively analyzed. The number of CMBs was calculated by the position of the CBMs according the different parts of CMBs( cortex-subcortical area,basal ganglia, thalamus,brain stem,cerebellum). And the association of numbers of CMBs with severity of hypertension,time of duration and control of blood pressure were analyzed. Results All the 150 cases have the existence of CMBs,round,symmetrical extremely low signal area,the boundary was more clear for isolated existence. A total of 526 CMBs was detected,mainly multiple,and mainly distributed in the deep areas such as basal ganglia( 35. 6%),thalamus( 30. 8%). There was significant difference on the number of CMBs among the severity of hypertension,time of duration and control of blood pressure( P 0. 05). The grade of CMBs had significant positive correlation with grade of lacunar infarction( r = 0. 269,P = 0. 0009). Conclusion SWI had high sensitivity to CMBs,it can obviously improve the CMBs detection,and the number of CMBs was obviously positive correlated with severity of hypertension. Strict blood pressure control in patients with hypertension combined CMBs,which can effectively reduce the formation of CMBs,stop the progress of the small blood vessel damage.