MR-image screening of cerebral microbleeds and analysis of related factors in cerebrovascular disease patients

Objectives To screen CMBs with MRI in patients with suspected cerebral vascular diseases, and explore the relations between CMBs degree and the hypertension severity degree and brain white matter changes. Methods 447 consecutive patients with suspected cerebral vascular disease were examined with T_2~* -GRE sequence to detect CMBs lesions. The number and location of microbleed lesions, white matter changes and blood pressure levels were recorded. According to whether there were CMBs,the patients were divided into two groups,CMBs group(95 cases) and non-CMBs group(352 cases). Results The foci in patients of CMBs group were in the lobes of brain( 42.09 % ), the thalami (19.77 % ), brainstem (14.41 % ), cerebellum (11.58 % ), periventricular area(6.21 % ) and basal ganglia(5. 65 % ). Compared with non-CMBs group,The age,hypertension, Binswanger image changes and the white matter lesions in the patients with CMBs had statistically significant difference. Logistic regression analysis indicated that the occurrence of CMBs was related to the factors such as hypertension and age. The severity of CMBs Was positively correlated with the severity of hypertension and cerebral white matter changes. Conclusions The incidence of CMBs in patients with cerehrovascular disease is high. The severity of CMBs is positively correlated with the severity of hypertension and cerebral white matter changes.