Clinical observation on the efficacy of buprenorphine for postoperative epidural analgesia in patients undergoing abdominal surgery

Objective To observe the efficacy of buprenorphine for postoperative epidural analgesia in patients undergoing abdominal surgery.Methods Sixty patients(ASAⅠ～Ⅱ) scheduled to undergo abdominal surgery under continuous epidural anesthesia were randomly divided into two groups:group Ⅰ(buprenorphine group,n=30) and group Ⅱ(morphine group,n=30).When closing the abdominal cavity,patients were given epidurally: buprenorphine(0.05mg,group Ⅰ) and morphine(2mg,group Ⅱ) were diluted for 10ml with 0.9%NaCl.The analgesic score at 4,8,12,24 and 36 hours after injection were assessed by Prine Hennry Scale.The MAP,HR,RR,SpO_2 and ECG were monitored.The adverse reaction were also recorded at the same time-points.Results In two groups,the analgesic score were less than 2,the superior rate of analgesia were 100%,the respiratory and circulative functions of patients were stable during analgesia.In group Ⅰthe incidence of adverse reaction is lower than that in group Ⅱ.Conclusion The postoperative analgesic effect of epidural injection of 0.05mg buprenorphine is definite.It is a safe,effective,simple and feasible method for postoperative pain.