Distribution and Prevalence of Human Papillomavirus(HPV) Genotypesin 2473 Cytological Samples Of Xinjiang Uyghur Women

Objective: To investigate the types distribution of human papillomavirus(HPV) in women in Xinjiang Uyghur women.Methods: Women between 30 and 59 were chosen in cluster stratified sampling from XiaPuTaoLe Town,Xinjiang and received a popu-lation-based cervical cancer screening.After consent,every woman was detected and genotyped HPV DNA by PCR and Gene Chip.Results: 2473 women were chosen.The total infection rate of HPV was 9.1%.The positive rate of HPV-16 infection was 6.9% among the High-Risk HPV indicating it was the most common infection.Other High-Risk HPV infection rates were ranked from high to low: HPV-59,HPV-56,HPV-18,HPV-33,HPV-58,HPV-51,HPV-31,HPV-45,HPV-52,HPV-35,HPV-39,HPV-68.HPV-11 was the most com-mon infection among the Low-Risk HPV types.Other Low-Risk HPV infection rates were ranked from high to low: HPV-42,HPV-43,HPV-6,HPV-53,HPV-66,HPV-73.HPV-44,-83,-MM4 were not detected.The multiple infection rate was 34.2%.Conclusion: HPV-16 was the most common types in the study population.The next most common types of HPV were HPV59,56,18,33.Xinjiang Uighur women had the relatively higher risk of suffering HPV59 infection indicating the specificity of HPV infection in Xinjiang Uighur women.