Distribution of Human Papillomavirus Types in Xinjiang Uyghur Women

Objective:To investigate the distribution of types of human papillomavirus(HPV) in Xinjiang Uyghur women.Methods:Women between 30 and 59 years old were selected in cluster stratified sampling from XiaPuTaoLe Town, Xinjiang, and received a population-based cervical cancer screening.After consent, HPV DNA in each collected sample was detected by PCR and Gene Chip.Results:Totally 2473 women were screened.The total infection rate of HPV was 9.1%.The positive rate of HPV-16 infection was 6.9% among the High-Risk HPV, indicating it was the most common infection.Other High-Risk HPV infection rates were ranked from high to low as HPV-59, HPV-56, HPV-18, HPV-33, HPV-58, HPV-51, HPV-31, HPV-45, HPV-52, HPV-35, HPV-39 and HPV-68.Furthermore, HPV-11 was the most common infection among the Low-Risk HPV types.Other Low-Risk HPV infection rates were ranked from high to low as HPV-42, HPV-43, HPV-6, HPV-53, HPV-66,and HPV-73.However, HPV-44, HPV-83 and HPV-MM4 were not detected.The multiple infection rate was 34.2%.Conclusion:HPV-16 was the most common types in Xinjiang Uyghur women.The next most common types of HPV were HPV59, 56, 18 and 33.Xinjiang Uighur women has the relatively higher risk of suffering HPV59 infection, indicating the specificity of HPV infection in Xinjiang Uighur women.