2011•Xiandai shengwu yixue jinzhanRequires access

Expression of PTEN and MTA1 and their Correlation in the Endometrial Cancer

G.Y. Ling

Abstract

Objective: To explore the expression of PTEN and MTA1 and their correlation in the endometrial cancer.Methods: In 130 cases of endometrial cancer and 40 cases of normal endometrial,the expression of PTEN and MTA1 was examined with immunohis-tochemistry SP method and their correlation.Results: The expression of PTEN and MTA1 in endometrial cancer was higher than that in normal endometrial.(P0.01).PTEN expression levels in endometrial cancer were inversely correlated with MTA1 protein.(r=-0.35,P0.05).Conclusion: Expression of PTEN expression and MTA1 is inversely correlated with the development and progression of en-dometrial cancer.

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Key concepts: PTEN, Endometrial cancer, Cancer, Correlation, Cancer research, Biology, Oncology, Medicine