Clinical Investigation on Treating Arteriosclerotic Cerebral Infarction Combined with Hyperlipemia by Prubucol

Objective:To study the effect of prubucol on the blood lipids level and prognosis in arteriosclerotic cerebral infarction associated with hyperlipidemia patients.Methods:Eighty-seven arteriosclerotic cerebral infarction combined with hyperlipidemia patients were randomly divided in to 2 groups:44 cases in treated group prescribed with prubucol 500mg bid/day for a course of 6 months.The follow-up study lasted for1year.Observe the changes in blood lipids and the occurrence of acute cardiocerebral vascular event.Results:The level of TC,LDL,TG and HDL increased significantly(P0.05),and the efficacy of treated group was superior to the control group obviously(P0.05).The results of follow-up study showed the numbers of cerebrovascular events in the treatment group were 12 times,and that of the control group were 15 times.Conclusion:Prubucol have curative effect affirmation to treat hyperlipdemia with few side-effect,and reduce the incidence of cerebrovascular diseases and cardiovascular diseases.It should be extended to the clinical use in primary and secondary prevention of arteriosclerotic cerebral infarction combined with hyperlipidemia.