2010•Inner Mongolia Medical JournalRequires access

Study of Thinprep Liquid Based Cytology Test in the Screening of Cervical Lesions in Erdos Area

Xianzhi Duan

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Abstract

Objective:Through investigating the Cancer of the cervix(CACX) incidence and epidemiologic feature of Erdos area in china,assess the value of thinprep liquid based cytology test(TCT)in diagnosis of cervical lesions.Methods:From Erdos area 18 071 cases of cervical lesions were detected and diagnosed with TCT.The samples of atypical squamous cells(ASC)and more severe than ASC lesions were classified into positive cases,then multi-cervix tissues were biopsied by colposcope.Compared with pathological examination results of cervical biopsies.Results:The postive rate of abnormal epithelial cells diagnosed by TCT was 5.77%.There were 2 cases(0.01%)of CA,61 cases(0.34%)of HSIL,221 cases(1.22%)0f LSIL,142 cases(0.79%)of ASC-H.426 cases with postive cytologic results received pathological examination,The pathological positive rates of CA,HSIL,LSIL and ASC-H were 100%,98.36%,57.92% and 64.79%,respectively.The coincident rate of two examination methods was 100% for CA,85.25% for HSIL,51.58% for LSIL and 47.18% for ASC-H.Conclusion:TCT applies to large scale screening of cervical lesions,three steps diagnosis can obviously elevate the detection rate of cervical lesions.The age of onset tends to get younger in cervical cancer and precancerous lesions.The morbidity rate of the cervical lesions and precancerous lesions among Mongolia woman are higher than that of Han woman.

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Objective:Through investigating the Cancer of the cervix(CACX) incidence and epidemiologic feature of Erdos area in china,assess the value of thinprep liquid based cytology test(TCT)in diagnosis of cervical lesions.Methods:From Erdos area 18 071 cases of cervical lesions were detected and diagnosed with TCT.The samples of atypical squamous cells(ASC)and more severe than ASC lesions were classified into positive cases,then multi-cervix tissues were biopsied by colposcope.Compared with pathological examination results of cervical biopsies.Results:The postive rate of abnormal epithelial cells diagnosed by TCT was 5.77%.There were 2 cases(0.01%)of CA,61 cases(0.34%)of HSIL,221 cases(1.22%)0f LSIL,142 cases(0.79%)of ASC-H.426 cases with postive cytologic results received pathological examination,The pathological positive rates of CA,HSIL,LSIL and ASC-H were 100%,98.36%,57.92% and 64.79%,respectively.The coincident rate of two examination methods was 100% for CA,85.25% for HSIL,51.58% for LSIL and 47.18% for ASC-H.Conclusion:TCT applies to large scale screening of cervical lesions,three steps diagnosis can obviously elevate the detection rate of cervical lesions.The age of onset tends to get younger in cervical cancer and precancerous lesions.The morbidity rate of the cervical lesions and precancerous lesions among Mongolia woman are higher than that of Han woman.

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Available abstract

Objective:Through investigating the Cancer of the cervix(CACX) incidence and epidemiologic feature of Erdos area in china,assess the value of thinprep liquid based cytology test(TCT)in diagnosis of cervical lesions.Methods:From Erdos area 18 071 cases of cervical lesions were detected and diagnosed with TCT.The samples of atypical squamous cells(ASC)and more severe than ASC lesions were classified into positive cases,then multi-cervix tissues were biopsied by colposcope.Compared with pathological examination results of cervical biopsies.Results:The postive rate of abnormal epithelial cells diagnosed by TCT was 5.77%.There were 2 cases(0.01%)of CA,61 cases(0.34%)of HSIL,221 cases(1.22%)0f LSIL,142 cases(0.79%)of ASC-H.426 cases with postive cytologic results received pathological examination,The pathological positive rates of CA,HSIL,LSIL and ASC-H were 100%,98.36%,57.92% and 64.79%,respectively.The coincident rate of two examination methods was 100% for CA,85.25% for HSIL,51.58% for LSIL and 47.18% for ASC-H.Conclusion:TCT applies to large scale screening of cervical lesions,three steps diagnosis can obviously elevate the detection rate of cervical lesions.The age of onset tends to get younger in cervical cancer and precancerous lesions.The morbidity rate of the cervical lesions and precancerous lesions among Mongolia woman are higher than that of Han woman.

Key concepts: Medicine, Pathological, Cervix, Cytology, Cervical cancer, Liquid-based cytology, Incidence (geometry), Gynecology

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