Clinical analysis of 82 cases of ankylosing spondylitis associated with uveitis

Objective To investigate the clinical characteristics and therapeutic effect of ankylosing spondylitis(As) associated with uveitis.Methods The clinical data of 82 patients of AS associated with uveitis were analyzed to review the clinical characteristics and therapeutic effect.Results The mean age of the patients was(34.99±8.28) years and 85.37% of the patients were male.HLA-B27 positivity was 87.80%.Scoring for uveitis was(5.56±2.04).After treating with non-steroids anti-inflammatory drugs,disease modifying drugs and local ophthalmologic treatment,the symptoms of uveitis got relieved,acuity of vision was improved and the inflammation of the eyes disappeared,and the back pain was relieved.Erythrocyte sedimentation rate,C-reactive protein(CRP),Bath Ankylosing Spondylitis Disease Activity Index(BASDAI) and Bath Ankylosing Spondylitis Functional Index(BASFI) decreased(P0.05).Conclusion AS associated with uveitis often affects young male,with mostly unilateral involved,and most of the patients are HLA-B27 positive.Prompt and potent treatment lead to satisfactory therapeutic effect and usually favorable prognosis.